Homogenization of human tissues via picosecond-infrared laser (PIRL) ablation

Analytics
Giving a closer view on the in-vivo composition of protein species as compared to mechanical homogenization Enzymatic protein modifications during tissue homogenization are responsible for changes of the in-vivo protein species composition. Cold vaporization of tissue by PIRL-DIVE is comparable with taking a snapshot at the time of the laser irradiation of the dynamic changes that occur continuously under...
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PIRL DIVE-extraction of proteins

Analytics
Ultrafast extraction of proteins from tissues using desorption by impulsive vibrational excitation. The extraction of proteins from tissue samples represents a critical and time-consuming step in every proteomic and protein analytical approach. In general, protein extraction includes a number of different experimental steps like homogenization, lyzation and protein isolation varying in dependence of tissue type and proteins of interest....
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